Nad CAS 53-84-9 Beta Nicotinamide Adenine Dinucleotide

• Customization: Available
• Function: Vitamins and Minerals Deficiency Drug, Antibiotic and Antimicrobial Agents
• Certification: GMP
• Model NO.: NAD
• Type: Analysis reagent
• State: Liquid
• Volatile: Not Volatile
• CAS: 53-84-9
• Transport Package: 25kg
• Specification: 99%
• Trademark: langyue
• Origin: Hunan
• HS Code: 2901
• Production Capacity: 30 Tons/Year

Product Description

NAD CAS 53-84-9 Beta Nicotinamide adenine dinucleotide

Product Information:

Product Name:	β-Nicotinamide adenine dinucleotide
Synonyms:	OSTEOPONTIN, GST FUSION;)-1-beta-d-ribofuranosylpyridiniumhydroxide,innersalt;adenine-nicotinamidedinucleotide; adenosine5’-(trihydrogendiphosphate),p’.fwdarw.’-esterwith3-(aminocarbonyl; Adenosine5’-(trihydrogendiphosphate),P’.fwdarw.5’-esterwith3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium,innersalt; beta-diphosphopyridine;cozymasei;enzopride
CAS:	53-84-9
MF:	C21H27N7O14P2
MW:	663.43
EINECS:	200-184-4

Product Description:

β-Nicotinamide adenine dinucleotide (NAD+) plays a major role in metabolism as a cofactor and mobile electron acceptor. NAD+ is a required oxidizing cosubstrate for many enzymes. It is reduced to NADH (Cat# N-035) which carries electrons to the electron transport chain for subsequent oxidative phorphorylation and ATP production. NAD+ is capable of donating ADP-ribose moieties to a protein, producing nicotinamide in the process. Sirtuin enzymes use NAD+ as a substrate to deacetylate proteins and direct activity between the nucleus and mitochondria. NAD+ is regenerated by fermentation and by oxidative phosphorylation.

 

Chemical Properties
Beta-Nicotinamide adenine dinucleotide is a hygroscopic white powder. It should be stored desiccated. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20°C.

Uses
β-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a c oenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleot ide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.

Application
β-Nicotinamide adenine dinucleotide (β-NAD) is a cofactor of alcohol dehydrogenase and acts as a neuromodulator and an inhibitory neurotransmitter in visceral smooth muscles. The NAD/NADH ratio has a role in the regulation of intracellular redox potential. It thereby influences metabolic reactions in vivo. It has been used for the preparation of deacetylated tubulin. It has also been used for UDP-glucose-6-hydrogenase (UGDH) enzyme activity assay of orital fibroblast cell lysates.

β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).

 

ITEM	SPECIFICATION	RESULT	Test Method
Appearance	White to off-white powder	Complies	Visual
Identification	Meet the requirements	Complies	HPLC
Water	≤5.0%	2.8%	Internal method
pH value	2.0-4.0	3.1	pH Meter
Solubility	Soluble in water	Complies	Internal method
Sodium content	≤1%	0.03%	Internal method
Total Heavy metals	≤10ppm	Complies	Atomic Absorption
Pb	≤0.5ppm	Complies	Atomic Absorption
As	≤0.5ppm	Complies	Atomic Absorption
Cd	≤0.5ppm	Complies	Atomic Absorption
Hg	≤0.5ppm	Complies	Atomic Absorption
Methanol	≤1.0%	Not detected	GC
Ethanol	≤2.0%	0.75%	GC
Total microbacterial count	≤1000CFU/g	Complies	CP2015
Yeast &Mould	≤100CFU/g	Complies	CP2015
Escherichia Coli presence	Negative	Negative	CP2015
Salmonella	Negative	Negative	CP2015
P. aeruginosa	Negative	Negative	CP2015
S. aureus	Negative	Negative	CP2015
Bile tolerant gram negative	Negative	Negative	USP
Purity	≥99.0%	99.4%	HPLC
Assay of β-NAD	≥99.0%(Cal. on dry basis)	99.5%	HPLC
Conclusion	The results conforms with the enterprise standard

Quality Control: 

We have advanced precision instruments and equipment ,so we can independently control product content, pesticide residue, physical and chemical properties, microorganisms, heavy metals and other quality indicators. Our goal is zero complaints.



We have our own plant base. Weeding by hand, no pesticides or herbicides used. Control quality from the source.




Packaging:
The product is packed in 25kg or 10kg fiber drum.
It should be stored in its original packing or in a suitable sealed container and kept in a clean and dry place. Storage conditions should preferably be a sheltered environment with limited temperature variations and low humidity levels. Direct contact with water or any other liquid will result in product caking. Under normal circumstances, the use of this product will not cause any undue health hazards. Precautions must be taken to prevent solid or liquid product to contact with skin or eyes.

Customization Service
R&D and Production: We specializes in the development of functional materials and has provided a number of development and improvement solutions.
Granular Production: Our granulation and superfine pulverization can improve bulk density to filling capsules and tablets. and increase water solubility.
Blending and Mixing