Nad CAS 53-84-9 β -Nicotinamide Adenine Dinucleotide

• Customization: Available
• Function: Vitamins and Minerals Deficiency Drug, Nutritional Therapeutics
• Certification: GMP
• Model NO.: 99%
• Grade Standard: USP
• Type: Analysis reagent
• State: Powder
• Volatile: Not Volatile
• CAS: 53-84-9
• Transport Package: 25kg
• Specification: 99%
• Trademark: langyue
• Origin: Hunan
• HS Code: 2901
• Production Capacity: 30 Tons/Year

Product Description

Product Name:	β-Nicotinamide adenine dinucleotide
Synonyms:	OSTEOPONTIN, GST FUSION;)-1-beta-d-ribofuranosylpyridiniumhydroxide,innersalt;adenine-nicotinamidedinucleotide;adenosine5'-(trihydrogendiphosphate),p'.fwdarw.'-esterwith3-(aminocarbonyl;Adenosine5'-(trihydrogendiphosphate),P'.fwdarw.5'-esterwith3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium,innersalt;beta-diphosphopyridine;cozymasei;enzopride
CAS:	53-84-9
MF:	C21H27N7O14P2
MW:	663.43
EINECS:	200-184-4

β-Nicotinamide adenine dinucleotide (NAD+) plays a major role in metabolism as a cofactor and mobile electron acceptor. NAD+ is a required oxidizing cosubstrate for many enzymes. It is reduced to NADH (Cat# N-035) which carries electrons to the electron transport chain for subsequent oxidative phorphorylation and ATP production. NAD+ is capable of donating ADP-ribose moieties to a protein, producing nicotinamide in the process. Sirtuin enzymes use NAD+ as a substrate to deacetylate proteins and direct activity between the nucleus and mitochondria. NAD+ is regenerated by fermentation and by oxidative phosphorylation.

 

Chemical Properties
Beta-Nicotinamide adenine dinucleotide is a hygroscopic white powder. It should be stored desiccated. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20°C.

Uses
β-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a c oenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleot ide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.

Application
β-Nicotinamide adenine dinucleotide (β-NAD) is a cofactor of alcohol dehydrogenase and acts as a neuromodulator and an inhibitory neurotransmitter in visceral smooth muscles. The NAD/NADH ratio has a role in the regulation of intracellular redox potential. It thereby influences metabolic reactions in vivo. It has been used for the preparation of deacetylated tubulin. It has also been used for UDP-glucose-6-hydrogenase (UGDH) enzyme activity assay of orital fibroblast cell lysates.

β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).

The testing center of our company is equipped with ULTRAVIOLET room, atom room, gas room, high efficiency liquid room, balance room, high temperature room, chemical room, bacteria examination room, stability laboratory, sample room and central laboratory. Coordinated, comprehensive, systematic and standardized testing of all raw materials, production water, intermediates and finished products to ensure that unqualified raw materials are not put into storage. Disqualified intermediates do not flow into the next process. Nonconforming finished products will not be shipped.
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We have our own plant base. Weeding by hand, no pesticides or herbicides used. Control quality from the source.




Packaging:
The product is packed in 25kg or 10kg fiber drum.
It should be stored in its original packing or in a suitable sealed container and kept in a clean and dry place. Storage conditions should preferably be a sheltered environment with limited temperature variations and low humidity levels. Direct contact with water or any other liquid will result in product caking. Under normal circumstances, the use of this product will not cause any undue health hazards. Precautions must be taken to prevent solid or liquid product to contact with skin or eyes.

Customization Service
R&D and Production: We specializes in the development of functional materials and has provided a number of development and improvement solutions.
Granular Production: Our granulation and superfine pulverization can improve bulk density to filling capsules and tablets. and increase water solubility.
Blending and Mixing