Gsh CAS 70-18-8 L-Glutathione Reduced Nutrional Supplement

• Customization: Available
• Function: Vitamins and Minerals Deficiency Drug, Antibiotic and Antimicrobial Agents
• Certification: GMP
• Model NO.: L-Glutathione reduced
• Type: Analysis reagent
• State: Liquid
• Volatile: Not Volatile
• CAS: 70-18-8
• Transport Package: 25kg
• Specification: 99%
• Trademark: langyue
• Origin: Hunan
• HS Code: 2901
• Production Capacity: 30 Tons/Year

Product Description

GSH CAS 70-18-8 L-Glutathione reduced nutrional supplement

Product Information:

Product Name:	Glutathione
Synonyms:	glutatiol;glutatione;glutide;glutinal;isethion;l-glutatione;N(N-L-.gamma.-Glutamyl-L-cysteinyl)glycine; n-(n-l-gamma-glutamyl-l-cysteinyl)-glycin
CAS:	70-18-8
MF:	C10H17N3O6S
MW:	307.32
EINECS:	200-725-4
Assay:	HPLC 99%
Package:	25kg/drum or customized
Shelf life:	24months
Storage:	Store in a cool, dry place, away from bright light and high temperature.

Reduced glutathione (GSH) is a crucial antioxidant that supports healthy liver function. It is found in high concentrations in
cellular systems and plays a crucial role in detoxification of various substances.

 

Glutathione (GSH) is a ubiquitous molecule found in many cells and tissues. The three amino acids present in GSH are glycine, cysteine, and glutamic acid.

Application
L-Glutathione (GSH) reduced has been used in the elution buffer to elute GST (glutathione S-transferase)-fused proteins using glutathione-agarose beads.[2][3] It has been used to prepare a standard curve for GSH analyses.[4]
May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Biochem/physiol Actions
Glutathione (GSH) forms conjugates with various metabolites and xenobiotics. It acts as an important co-factor for various enzymes. GSH is involved in many metabolic and signaling pathways. Glutathione functions as a thiol buffer for cellular proteins like thioredoxins and metallothioneins. GSH is also involved in the regeneration of antioxidants like tocopherols and ascorbate.

Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

 

ITEM	SPECIFICATION	RESULT	Test Method
Appearance	White powder	Complies	Visual
Odor and taste	Characteristic	Complies	Sensory
Identification	Meet requirements	Complies	IR
Loss on drying	≤0.5%	0.32%	USP 40
Residue on ignition	≤0.1%	0.04%	USP 40
Optical Rotation	[α]D20: -15.5°~-17.5°°	-15.8°°	USP 40
Solubility	Soluble in water, insoluble in ethanol	Complies	Visual
Bulk density	0.3~0.6g/ml	0.43g/ml	CP2015
Tapped density	0.4~0.9g/ml	0.55g/ml	CP2015
Appearance of solution	Clear and colorless	Complies	Visual
Total Heavy metals	≤10ppm	Complies	USP 40
Pb	≤3ppm	Complies	USP 40
As	≤2ppm	Complies	USP 40
Cd	≤1ppm	Complies	USP 40
Hg	≤1ppm	Complies	USP 40
Iron	≤10ppm	Complies	USP 40
Chloride	≤200ppm	Complies	USP 40
Ammonium	≤200ppm	Complies	USP 40
Sulfate	≤300ppm	Complies	USP 40
Total microbacterial count	≤100CFU/g	Complies	CP2015
Yeast &Mould	≤10CFU/g	Complies	CP2015
Escherichia Coli presence	Negative	Negative	CP2015
Salmonella	Negative	Negative	CP2015
S. aureus	Negative	Negative	CP2015
P. aeruginosa	Negative	Negative	CP2015
Total impurities	≤2.0%	1.1%	USP 40
Individual impurity (L-Glutathione Oxidized)	≤1.5%	0.9%	USP 40
Assay	98.0%~101%	98.8%	USP 40
Conclusion	The results conforms with the USP 40 standard

Quality Control: 

We have advanced precision instruments and equipment ,so we can independently control product content, pesticide residue, physical and chemical properties, microorganisms, heavy metals and other quality indicators. Our goal is zero complaints.



We have our own plant base. Weeding by hand, no pesticides or herbicides used. Control quality from the source.




Packaging:
The product is packed in 25kg or 10kg fiber drum.
It should be stored in its original packing or in a suitable sealed container and kept in a clean and dry place. Storage conditions should preferably be a sheltered environment with limited temperature variations and low humidity levels. Direct contact with water or any other liquid will result in product caking. Under normal circumstances, the use of this product will not cause any undue health hazards. Precautions must be taken to prevent solid or liquid product to contact with skin or eyes.

Customization Service
R&D and Production: We specializes in the development of functional materials and has provided a number of development and improvement solutions.
Granular Production: Our granulation and superfine pulverization can improve bulk density to filling capsules and tablets. and increase water solubility.
Blending and Mixing