USP Rosuvastatin Calcium CAS 147098-20-2

• Function: Regulating Water and Salt, Electrolyte and Acid-Base Balance of Medicine
• Certification: GMP
• Grade Standard: Medicine Grade
• Type: Chemical Reagent
• State: Powder
• Volatile: Not Volatile
• Model NO.: 99%
• CAS: 147098-20-2
• Transport Package: 25kg
• Specification: 99%
• Trademark: langyue
• Origin: Hunan
• HS Code: 2901
• Production Capacity: 30 Tons/Year

Product Description

Rosuvastatin Calcium

Product Information:

Other name:CRESTOR; ROSUVASTATIN CA; ROSUVASTATIN CALCIUM;Fortius; Rostar; Rosuvastatin hemicalcium; Rosuvastain Calcium
CAS: 147098-20-2
Molecular Formula:C44H54CaF2N6O12S2
Molecular Weight:1001.13
Source: Synthetic
Appearance: White powder
Melting point:122ºC
Assay :≥99.0%
Heavy metals: <10PPM

Product Description:

Rosuvastatin is a selective reductase inhibitor of HMG-CoA.HMG-CoA reductase inhibitors are rate-limiting enzymes that convert 3-hydroxy-3-methylglutaryl coenzyme A to valerate, the precursor of cholesterol.The main site of action of rosuvastatin is the liver, the organ targeted for lowering cholesterol.Rosuvastatin increased the number of receptors on the surface of liver LDL cells, promoted LDL absorption and catabolism, and inhibited the liver synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles.

Product Description:

 

Lappaconitine hydrobromide, a diterpene alkaloid, is a drug for the treatment of cardiac arrhythmias. IC50 value: Target: A natural product for anti-cardiac arrhythmias In vitro: Lappaconitine hydrobromide was found to exert an inhibitory effect on inward tetrodotoxin-sensitive sodium currents without changing their voltage dependence [1]. In vivo: The effect of Lappaconitine hydrobromide on aconitine--induced arrhythmias is due to modulation of genes encoding Na(+)-, K(+)-, Ca(2+)-channels, conducting ionic currents (I(Na), I(to), I(Ks), I(K1), I(CaT)), which are involved in the formation of different phases of the action potential [2]. Lappaconitine hydrobromide was found to be beneficial both in ventricular and supraventricular premature beats. Oral allapinine usually showed its effect 40-60 minutes following its administration, its maximum action being 4-5 hours later, its duration was some 8 hours. The optimal dose of the drug amounted to 75 mg/day [3].

Uses, benefits, Side Effects
1.Doxepin, a psychotropic drug, is a tricyclic antidepressant with anti-anxiety activity
2.Doxepin inhibits the reuptake of serotonin and norepinephrine.Its reuptake of dopamine is negligible.Doxepin antagonizes various receptors, including H1, H2, 5-HT1, 5-HT2, α1-adrenergic and Mach
3.For the treatment of depression and anxiety neurosis

Application
Anti-depression, used for depression and neurosis

Quality Control: 
We have advanced precision instruments and equipment ,so we can independently control product content, pesticide residue, physical and chemical properties, microorganisms, heavy metals and other quality indicators. Our goal is zero complaints.
We have our own plant base. Weeding by hand, no pesticides or herbicides used. Control quality from the source.




Package:
1kg,5kg in aluminum bag. 25kg per drum.
Storage:
Store at below 25ºC temperature and away from light.
Shipping:
Bulk goods ship by sea or air. Small quantity shipped via FedEx, DHL and others courier.