Lappaconitine Hydrobromide CAS: 97792-45-5 Lappaconitine Hbr; Allapinine; Allapinine Hydrobromide

• Certification: GMP, ISO 9001, USP, ISO, HACCP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >98%
• Assay Method: HPLC
• Application Form: Suppository, Capsule
• Model NO.: CAS: 97792-45-5
• Application: Food, Health Care Products, Medicine
• CAS No.: 97792-45-5
• Appearance: White Powder
• Molecular Formula: C32h45brn2o8
• Storage: Below 25ºC Temperature and Away From Light
• Shelf Life: 2 Years
• Transport Package: 25kgs/Drum
• Specification: ≥ 98.0%
• Origin: China
• HS Code: 29329990
• Production Capacity: 5000kgs/Per Month

Product Description

Lappaconitine hydrobromide

Product Information:

Other name: LAPPACONITINE HBR; ALLAPININE; ALLAPININE HYDROBROMIDE;(1-alpha,14-alpha,16-beta)-monohydrobromide
CAS:97792-45-5
Molecular Formula:C32H45BrN2O8 
Molecular Weight:: 665.61
Source: Synthetic
Appearance: White powder
Melting point:194~202ºC
Assay :≥98.0%
Heavy metals: <10PPM

 

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Product Description:

Lappaconitine hydrobromide, a diterpene alkaloid, is a drug for the treatment of cardiac arrhythmias. IC50 value: Target: A natural product for anti-cardiac arrhythmias In vitro: Lappaconitine hydrobromide was found to exert an inhibitory effect on inward tetrodotoxin-sensitive sodium currents without changing their voltage dependence [1]. In vivo: The effect of Lappaconitine hydrobromide on aconitine--induced arrhythmias is due to modulation of genes encoding Na(+)-, K(+)-, Ca(2+)-channels, conducting ionic currents (I(Na), I(to), I(Ks), I(K1), I(CaT)), which are involved in the formation of different phases of the action potential [2]. Lappaconitine hydrobromide was found to be beneficial both in ventricular and supraventricular premature beats. Oral allapinine usually showed its effect 40-60 minutes following its administration, its maximum action being 4-5 hours later, its duration was some 8 hours. The optimal dose of the drug amounted to 75 mg/day [3].
Uses, benefits, Side Effects
   This product has local anesthesia, cooling, antipyretic and anti-inflammatory effect
   It also has antiepileptic, anti-tumor, anti-bacterial, anti-oxidation and immunomodulation effects. Hypericarbromide can control epileptic activity by inhibiting hippocampal neuronal activity.

Application
For more than moderate pain,It is a non-addictive analgesic with strong analgesic effect
Quality Control: 
The testing center of our company is equipped with ULTRAVIOLET room, atom room, gas room, high efficiency liquid room, balance room, high temperature room, chemical room, bacteria examination room, stability laboratory, sample room and central laboratory. Coordinated, comprehensive, systematic and standardized testing of all raw materials, production water, intermediates and finished products to ensure that unqualified raw materials are not put into storage. Disqualified intermediates do not flow into the next process. Nonconforming finished products will not be shipped.

Package:
1kg,5kg in aluminum bag. 25kg per drum.
Storage:
Store at below 25ºC temperature and away from light.
Shipping:
Bulk goods ship by sea or air. Small quantity shipped via FedEx, DHL and others courier.

Customization Service
R&D and Production: We specializes in the development of functional materials and has provided a number of development and improvement solutions.
Granular Production: Our granulation and superfine pulverization can improve bulk density to filling capsules and tablets. and increase water solubility.
Blending and Mixing

Q&A.

Q1. Are you a factory or a trading company?
A: We are a factory. Welcome to visit us.
Q2:Can I get a sample?
A: Of course. For most products we can provide a free sample, while the shipping cost should undertake by your side.
Q3:What's your MOQ?
A:Mostly MOQ is 1kg, but we also accept less quantity like 100g on the condition that a sample charge is 100% paid.
Q4:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,we'd like to accept T/T, Western Union.
Q5: What's your delivery time?
A:We will make delivery within 3 to 5 working days after payment confirmed.
Q6:How long does it take to the goods arrived ?
A:It is Depending on your location,
For small order, please expect 5-7 days by DHL,TNT, FEDEX.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.
Q7:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.


Quality Control
We have advanced precision instruments and equipment ,so we can independently control product content, pesticide residue, physical and chemical properties, microorganisms, heavy metals and other quality indicators. Our goal is zero complaints.

OEM Service
According to your requirements, we can customize capsules, soft capsules, tablets and mask.
1. We supply raw material and mixed ingredients according to your formula.
2. We offer the different package according to your requirements.
3. Customrized Private lable.